Ontology highlight
ABSTRACT:
SUBMITTER: Ni Y
PROVIDER: S-EPMC5971487 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Ni Yin Y Song Caiyun C Jin Shuqing S Chen Zhoufeng Z Ni Ming M Han Lu L Wu Jiansheng J Jin Yin Y
The Journal of international medical research 20170424 2
Objective To explore stable and functional microRNA (miRNA)-disease relationships using a genome-wide expression profile pattern matching strategy. Methods We applied the ranked microarray pattern matching strategy Gene Set Enrichment Analysis to identify miRNA permutations with similar expression patterns to diseases. We also used quantitative reverse transcription PCR to validate the predicted expression levels of miRNAs in three diseases: inflammatory bowel disease (IBD), oesophageal cancer, ...[more]