Ontology highlight
ABSTRACT:
SUBMITTER: Thompson ER
PROVIDER: S-EPMC4539664 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Thompson Ella R ER Gorringe Kylie L KL Rowley Simone M SM Wong-Brown Michelle W MW McInerny Simone S Li Na N Trainer Alison H AH Devereux Lisa L Doyle Maria A MA Li Jason J Lupat Richard R Delatycki Martin B MB Mitchell Gillian G James Paul A PA Scott Rodney J RJ Campbell Ian G IG
Breast cancer research : BCR 20150819
<h4>Introduction</h4>PALB2 is emerging as a high-penetrance breast cancer predisposition gene in the order of BRCA1 and BRCA2. However, large studies that have evaluated the full gene rather than just the most common variants in both cases and controls are required before all truncating variants can be included in familial breast cancer variant testing.<h4>Methods</h4>In this study we analyse almost 2000 breast cancer cases sourced from individuals referred to familial cancer clinics, thus repre ...[more]