Ontology highlight
ABSTRACT:
SUBMITTER: Lalevee S
PROVIDER: S-EPMC4540200 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Lalevée S S Lapaire O O Bühler M M
Cell death & disease 20140904
Preeclampsia is a severe pregnancy-related disorder and a leading cause of maternal and fetal mortality worldwide. Early identification of patients with an increased risk for preeclampsia is thus one of the most important goals in obstetrics. Here we identify two related human microRNAs as potential biomarkers to detect at-risk pregnancies. We demonstrate that miR455-3P and miR455-5P are significantly downregulated in placentas from preeclampsia patients, whereas other placenta-specific microRNA ...[more]