Ontology highlight
ABSTRACT:
SUBMITTER: Iglesias NG
PROVIDER: S-EPMC4543523 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Iglesias Nestor G NG Mondotte Juan A JA Byk Laura A LA De Maio Federico A FA Samsa Marcelo M MM Alvarez Cecilia C Gamarnik Andrea V AV
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Dengue viruses cause the most important human viral disease transmitted by mosquitoes. In recent years, a great deal has been learned about molecular details of dengue virus genome replication; however, little is known about genome encapsidation and the functions of the viral capsid protein. During infection, dengue virus capsid progressively accumulates around lipid droplets (LDs) by an unknown mechanism. Here, we examined the process by which the viral capsid is transported from the endoplasmi ...[more]