Ontology highlight
ABSTRACT:
SUBMITTER: Fromme R
PROVIDER: S-EPMC4547822 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Fromme Raimund R Ishchenko Andrii A Metz Markus M Chowdhury Shatabdi Roy SR Basu Shibom S Boutet Sébastien S Fromme Petra P White Thomas A TA Barty Anton A Spence John C H JC Weierstall Uwe U Liu Wei W Cherezov Vadim V
IUCrJ 20150804 Pt 5
Serial femtosecond crystallography (SFX) at X-ray free-electron lasers (XFELs) enables high-resolution protein structure determination using micrometre-sized crystals at room temperature with minimal effects from radiation damage. SFX requires a steady supply of microcrystals intersecting the XFEL beam at random orientations. An LCP-SFX method has recently been introduced in which microcrystals of membrane proteins are grown and delivered for SFX data collection inside a gel-like membrane-mimeti ...[more]