Ontology highlight
ABSTRACT:
SUBMITTER: Andersson R
PROVIDER: S-EPMC6779076 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Andersson Rebecka R Safari Cecilia C Båth Petra P Bosman Robert R Shilova Anastasya A Dahl Peter P Ghosh Swagatha S Dunge Andreas A Kjeldsen-Jensen Rasmus R Nan Jie J Shoeman Robert L RL Kloos Marco M Doak R Bruce RB Mueller Uwe U Neutze Richard R Brändén Gisela G
Acta crystallographica. Section D, Structural biology 20191001 Pt 10
Serial crystallography is having an increasing impact on structural biology. This emerging technique opens up new possibilities for studying protein structures at room temperature and investigating structural dynamics using time-resolved X-ray diffraction. A limitation of the method is the intrinsic need for large quantities of well ordered micrometre-sized crystals. Here, a method is presented to screen for conditions that produce microcrystals of membrane proteins in the lipidic cubic phase us ...[more]