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Monitoring the cytosolic entry of cell-penetrating peptides using a pH-sensitive fluorophore.


ABSTRACT: We report a simple, effective method to assess the cytosolic delivery efficiency and kinetics of cell-penetrating peptides using a pH-sensitive fluorescent probe, naphthofluorescein.

SUBMITTER: Qian Z 

PROVIDER: S-EPMC4550085 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature

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Monitoring the cytosolic entry of cell-penetrating peptides using a pH-sensitive fluorophore.

Qian Ziqing Z   Dougherty Patrick G PG   Pei Dehua D  

Chemical communications (Cambridge, England) 20150201 11


We report a simple, effective method to assess the cytosolic delivery efficiency and kinetics of cell-penetrating peptides using a pH-sensitive fluorescent probe, naphthofluorescein. ...[more]

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