Ontology highlight
ABSTRACT:
SUBMITTER: Man XY
PROVIDER: S-EPMC4554915 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Man Xiao-Yong XY Chen Xi-Bei XB Li Wei W Landeck Lilla L Dou Ting-Ting TT Chen Jia-Qi JQ Zhou Jiong J Cai Sui-Qing SQ Zheng Min M
Open biology 20150801 8
Psoriasis is similar to endpoints of epithelial-mesenchymal transition (EMT), a process of epithelial cells transformed into fibroblast-like cells. The molecular epithelial and mesenchymal markers were analysed in psoriatic keratinocytes. No obvious alteration of epithelial markers E-cadherin (E-cad), keratin 10 (K10), K14 and K16 was detected in psoriatic keratinocytes. However, significantly increased expression of Vim, FN, plasminogen activator inhibitor 1 (PAI-1) and Slug was seen. IL-17A an ...[more]