Ontology highlight
ABSTRACT:
SUBMITTER: Wang Y
PROVIDER: S-EPMC4557127 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Wang Yaping Y Wu Peng P Lin Rufeng R Rong Liucheng L Xue Yao Y Fang Yongjun Y
Scientific reports 20150902
Long non-coding RNA (lncRNA) was referred to be participating in various malignant tumors. Location based analysis of the mechanism in lncRNA and genes have been highly focused. In this study, we reported that lncRNA named NALT which was located near NOTCH1 within 100 bp away. We confirmed that up-regulation of NALT associating with NOTCH1 in human samples. Increased expression of NALT dramatically promoted cell proliferation in cell lines via CCK8 assay and EDU stain. Further xenograft tumor al ...[more]