Ontology highlight
ABSTRACT:
SUBMITTER: Bicknell BA
PROVIDER: S-EPMC4557358 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Bicknell Brendan A BA Dayan Peter P Goodhill Geoffrey J GJ
Nature communications 20150619
Many biological processes rely on the ability of cells to measure local ligand concentration. However, such measurements are constrained by noise arising from diffusion and the stochastic nature of receptor-ligand interactions. It is thus critical to understand how accurately, in principle, concentration measurements can be made. Previous theoretical work has mostly investigated this in 3D under the simplifying assumption of an unbounded domain of diffusion, but many biological problems involve ...[more]