Ontology highlight
ABSTRACT:
SUBMITTER: Pfaller CK
PROVIDER: S-EPMC4557643 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Pfaller Christian K CK Cattaneo Roberto R Schnell Matthias J MJ
Virology 20150218
The order Mononegavirales includes five families: Bornaviridae, Filoviridae, Nyamaviridae, Paramyxoviridae, and Rhabdoviridae. The genome of these viruses is one molecule of negative-sense single strand RNA coding for five to ten genes in a conserved order. The RNA is not infectious until packaged by the nucleocapsid protein and transcribed by the polymerase and co-factors. Reverse genetics approaches have answered fundamental questions about the biology of Mononegavirales. The lack of icosahedr ...[more]