Ontology highlight
ABSTRACT:
SUBMITTER: Novak AJ
PROVIDER: S-EPMC4558593 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Novak A J AJ Asmann Y W YW Maurer M J MJ Wang C C Slager S L SL Hodge L S LS Manske M M Price-Troska T T Yang Z-Z ZZ Zimmermann M T MT Nowakowski G S GS Ansell S M SM Witzig T E TE McPhail E E Ketterling R R Feldman A L AL Dogan A A Link B K BK Habermann T M TM Cerhan J R JR
Blood cancer journal 20150828
Lack of remission or early relapse remains a major clinical issue in diffuse large B-cell lymphoma (DLBCL), with 30% of patients failing standard of care. Although clinical factors and molecular signatures can partially predict DLBCL outcome, additional information is needed to identify high-risk patients, particularly biologic factors that might ultimately be amenable to intervention. Using whole-exome sequencing data from 51 newly diagnosed and immunochemotherapy-treated DLBCL patients, we eva ...[more]