Ontology highlight
ABSTRACT:
SUBMITTER: de Oliveira-Junior LC
PROVIDER: S-EPMC4568325 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
de Oliveira-Júnior Luiz Carlos LC Araújo Santos Fabiana de Almeida Fde A Goulart Luiz Ricardo LR Ueira-Vieira Carlos C
BioMed research international 20150831
Autoantibodies (aAb) associated with Alzheimer's disease (AD) have not been sufficiently characterized and their exact involvement is undefined. The use of information technology and computerized analysis with phage display technology was used, in the present research, to map the epitope of putative self-antigens in AD patients. A 12-mer random peptide library, displayed on M13 phages, was screened using IgG from AD patients with two repetitions. Seventy-one peptides were isolated; however, only ...[more]