Ontology highlight
ABSTRACT:
SUBMITTER: Mendoza-Santiesteban CE
PROVIDER: S-EPMC4568758 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Mendoza-Santiesteban Carlos E CE Palma Jose-Alberto JA Martinez Jose J Norcliffe-Kaufmann Lucy L Hedges Thomas R TR Kaufmann Horacio H
Movement disorders : official journal of the Movement Disorder Society 20150911 14
<h4>Background</h4>Objective measures of disease progression that can be used as endpoints in clinical trials of MSA are necessary. We studied retinal thickness in patients with MSA and assessed changes over time to determine its usefulness as an imaging biomarker of disease progression.<h4>Methods</h4>This was a cross-sectional study including 24 patients with MSA, 20 with PD, and 35 controls, followed by a longitudinal study of 13 MSA patients. Patients were evaluated with high-definition opti ...[more]