Ontology highlight
ABSTRACT:
SUBMITTER: Marme F
PROVIDER: S-EPMC4569194 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Marmé Frederik F Schneeweiss Andreas A
Breast care (Basel, Switzerland) 20150624 3
Triple-negative breast cancer (TNBC) is a heterogeneous disease comprised of several biologically distinct subtypes. However, treatment is currently mainly relying on chemotherapy as there are no targeted therapies specifically approved for TNBC. Despite initial responses to chemotherapy, resistance frequently and rapidly develops and metastatic TNBC has a poor prognosis. New targeted approaches are, therefore, urgently needed. Currently, bevacizumab, a monoclonal anti-vascular endothelial growt ...[more]