How to outsmart NK cell tolerance.
Ontology highlight
ABSTRACT:
SUBMITTER: Terszowski G
PROVIDER: S-EPMC4570122 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Publications
How to outsmart NK cell tolerance.
Terszowski Grzegorz G Klein Christian C Schmied Laurent L Stern Martin M
Oncoimmunology 20150402 9
Immune tolerance induced by regulatory mechanisms is an integral and fundamental part of immunity. In therapeutic settings, however, tolerance may significantly limit efficacy. Here, we summarize possible strategies to enhance therapeutic antibody dependent cellular cytotoxicity by overcoming NK cell tolerance. ...[more]
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