Dataset Information

Lifestyle-Related Factors and Atopy in Seven Danish Population-Based Studies from Different Time Periods.

ABSTRACT:

Background

The prevalence of allergic respiratory disease tends to increase in populations that adopt the so-called Westernized lifestyle. We investigated the association between atopy and several possible lifestyle-related factors in seven Danish population-based studies.

Methods

A total of 20048 persons participated in the seven studies. We used logistic regression to analyse the associations between possible determinants and atopy defined as serum specific IgE or skin prick test positivity against inhalant allergens. Associations were expressed as odds ratios (ORs) with 95% confidence intervals (95% CIs). In addition, individual participant data meta-analyses were performed.

Results

Atopy was significantly associated with younger age (OR per 1 year increase in age: 0.97; 95% CI: 0.97, 0.98); male sex (OR for males versus females: 1.34; 95% CI: 1.24, 1.45), heavy drinking (OR for heavy drinkers versus light drinkers: 1.15; 95% CI: 1.04, 1.27), never smoking (OR for current versus never smokers: 0.73; 95% CI: 0.67, 0.80), and higher educational level (OR for educated versus uneducated: 1.27; 95% CI: 1.15, 1.41). Atopy was not associated with blood pressure, serum total cholesterol, physical activity or body mass except in women only, where we found a positive association (OR for obese vs. normal weight: 1.18; 95% CI: 1.00, 1.39) with ptrend = 0.032.

Conclusions

Of interest for preventive purposes, we found that atopy was associated with some of the reversible lifestyle-related factors that characterize a Westernized lifestyle.

SUBMITTER: Skaaby T

PROVIDER: S-EPMC4570778 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

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Publications

Lifestyle-Related Factors and Atopy in Seven Danish Population-Based Studies from Different Time Periods.

Skaaby Tea T Husemoen Lise Lotte Nystrup LL Thuesen Betina Heinsbæk BH Jørgensen Torben T Linneberg Allan A

PloS one 20150915 9

<h4>Background</h4>The prevalence of allergic respiratory disease tends to increase in populations that adopt the so-called Westernized lifestyle. We investigated the association between atopy and several possible lifestyle-related factors in seven Danish population-based studies.<h4>Methods</h4>A total of 20048 persons participated in the seven studies. We used logistic regression to analyse the associations between possible determinants and atopy defined as serum specific IgE or skin prick tes ...[more]

PMID: 26372449

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Dataset Information

Lifestyle-Related Factors and Atopy in Seven Danish Population-Based Studies from Different Time Periods.

Background

Methods

Results

Conclusions

Publications

Lifestyle-Related Factors and Atopy in Seven Danish Population-Based Studies from Different Time Periods.

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