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Transient absorption microscopy of gold nanorods as spectrally orthogonal labels in live cells.

ABSTRACT: Gold nanorods (AuNRs) have shown great potential as bio-compatible imaging probes in various biological applications. Probing nanomaterials in live cells is essential to reveal the interaction between them. In this study, we used a transient absorption microscope to selectively image AuNRs in live cells. The transient absorption signals were monitored through lock-in amplification. This provides a new way of observing AuNRs with no interference from background autofluorescence.

SUBMITTER: Chen T

PROVIDER: S-EPMC4571198 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature

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Transient absorption microscopy of gold nanorods as spectrally orthogonal labels in live cells.

Chen Tao T Chen Shouhui S Zhou Jihan J Liang Dehai D Chen Xiaoyuan X Huang Yanyi Y

Nanoscale 20140807 18

Gold nanorods (AuNRs) have shown great potential as bio-compatible imaging probes in various biological applications. Probing nanomaterials in live cells is essential to reveal the interaction between them. In this study, we used a transient absorption microscope to selectively image AuNRs in live cells. The transient absorption signals were monitored through lock-in amplification. This provides a new way of observing AuNRs with no interference from background autofluorescence. ...[more]

PMID: 25098209

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