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Identification of NDM-1 in a Putatively Novel Acinetobacter Species ("NB14") Closely Related to Acinetobacter pittii.


ABSTRACT: In this study, we describe the molecular characterization of a plasmid-located blaNDM-1 harbored by an Acinetobacter clinical isolate recovered from a patient in Turkey that putatively constitutes a novel Acinetobacter species, as shown by its distinct ARDRA (amplified 16S ribosomal DNA restriction analysis) profile and molecular sequencing techniques. blaNDM-1 was carried by a conjugative plasmid widespread among non-baumannii Acinetobacter isolates, suggesting its potential for dissemination before reaching more clinically relevant Acinetobacter species.

SUBMITTER: Espinal P 

PROVIDER: S-EPMC4576105 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature

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Identification of NDM-1 in a Putatively Novel Acinetobacter Species ("NB14") Closely Related to Acinetobacter pittii.

Espinal Paula P   Mosqueda Noraida N   Telli Murat M   van der Reijden Tanny T   Rolo Dora D   Rolo Dora D   Fernández-Orth Dietmar D   Dijkshoorn Lenie L   Roca Ignasi I   Vila Jordi J  

Antimicrobial agents and chemotherapy 20150810 10


In this study, we describe the molecular characterization of a plasmid-located blaNDM-1 harbored by an Acinetobacter clinical isolate recovered from a patient in Turkey that putatively constitutes a novel Acinetobacter species, as shown by its distinct ARDRA (amplified 16S ribosomal DNA restriction analysis) profile and molecular sequencing techniques. blaNDM-1 was carried by a conjugative plasmid widespread among non-baumannii Acinetobacter isolates, suggesting its potential for dissemination b  ...[more]

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