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DisVis: quantifying and visualizing accessible interaction space of distance-restrained biomolecular complexes.

ABSTRACT: We present DisVis, a Python package and command line tool to calculate the reduced accessible interaction space of distance-restrained binary protein complexes, allowing for direct visualization and quantification of the information content of the distance restraints. The approach is general and can also be used as a knowledge-based distance energy term in FFT-based docking directly during the sampling stage.The source code with documentation is freely available from https://github.com/haddocking/disvis.a.m.j.j.bonvin@uu.nlSupplementary data are available at Bioinformatics online.

SUBMITTER: van Zundert GC

PROVIDER: S-EPMC4576694 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature

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DisVis: quantifying and visualizing accessible interaction space of distance-restrained biomolecular complexes.

van Zundert G C P GC Bonvin A M J J AM

Bioinformatics (Oxford, England) 20150529 19

<h4>Unlabelled</h4>We present DisVis, a Python package and command line tool to calculate the reduced accessible interaction space of distance-restrained binary protein complexes, allowing for direct visualization and quantification of the information content of the distance restraints. The approach is general and can also be used as a knowledge-based distance energy term in FFT-based docking directly during the sampling stage.<h4>Availability and implementation</h4>The source code with document ...[more]

PMID: 26026169

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