Ontology highlight
ABSTRACT:
SUBMITTER: Dukal H
PROVIDER: S-EPMC4579500 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Dukal Helene H Frank Josef J Lang Maren M Treutlein Jens J Gilles Maria M Wolf Isabell Ac IA Krumm Bertram B Massart Renaud R Szyf Moshe M Laucht Manfred M Deuschle Michael M Rietschel Marcella M Witt Stephanie H SH
Borderline personality disorder and emotion dysregulation 20150415
<h4>Background</h4>Research has demonstrated an association between exposure to early life stress and an increased risk of psychiatric disorders in later life, in particular depression. However, the mechanism through which early life stress contributes to disease development remains unclear. Previous studies have reported an association between early life stress and altered methylation of the serotonin transporter gene (SLC6A4), a key candidate gene for several psychiatric disorders. These diffe ...[more]