Electrochemical Studies of Morpholino-DNA Surface Hybridization.
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ABSTRACT:
SUBMITTER: O'Connor R
PROVIDER: S-EPMC4579539 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Publications
Electrochemical Studies of Morpholino-DNA Surface Hybridization.
O'Connor R R Tercero N N Qiao W W Levicky R R
ECS transactions 20110101 7
Surface hybridization, in which nucleic acids from solution bind to complementary "probe" strands immobilized on a solid support, is widely used to analyze composition of nucleic acid mixtures. Most often, detection is accomplished with fluorescent techniques whose sensitivity can be extended down to individual molecules. Applications, however, benefit as much if not more from convenience, accuracy, and affordability of the diagnostic test. By eliminating the need for fluorescent labeling and mo ...[more]
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