Ontology highlight
ABSTRACT:
SUBMITTER: Misra S
PROVIDER: S-EPMC4581573 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Misra Suniti S Hascall Vincent C VC Atanelishvili Ilia I Moreno Rodriguez Ricardo R Markwald Roger R RR Ghatak Shibnath S
International journal of cell biology 20150910
The outcome of patients with cancer has improved significantly in the past decade with the incorporation of drugs targeting cell surface adhesive receptors, receptor tyrosine kinases, and modulation of several molecules of extracellular matrices (ECMs), the complex composite of collagens, glycoproteins, proteoglycans, and glycosaminoglycans that dictates tissue architecture. Cancer tissue invasive processes progress by various oncogenic strategies, including interfering with ECM molecules and th ...[more]