MicroRNA levels quantified in whole blood varies from PBMCs.
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ABSTRACT:
SUBMITTER: Atarod S
PROVIDER: S-EPMC4582824 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Publications
MicroRNA levels quantified in whole blood varies from PBMCs.
Atarod Sadaf S Smith Hannah H Dickinson Anne A Wang Xiao-Nong XN
F1000Research 20140805
MicroRNAs are non-coding RNAs that negatively regulate mRNA expression and play significant roles in both health and disease. Differential microRNA expression has been used to aid diagnosis and discriminate disease stages. The accuracy and reliability of microRNA expression measurement is of utmost importance. Quantification of microRNA expression in human peripheral blood is commonly detected using total RNA extracted via different methods. To date, no convincing data are available showing whet ...[more]
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