Ontology highlight
ABSTRACT:
SUBMITTER: Rostoker R
PROVIDER: S-EPMC4583690 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Rostoker Ran R Jayaprakash Anitha D AD Sachidanandam Ravi R LeRoith Derek D
Genomics data 20150709
CD24 is an anchored cell surface marker that is highly expressed in cancer cells (Lee et al., 2009) and its expression is associated with poorer outcome of cancer patients (Kristiansen et al., 2003). Phenotype comparison between two subpopulations derived from the Mvt1 cell line, CD24(-) cells (with no CD24 cell surface expression) and the CD24(+) cells, identified high tumorigenic capacity for the CD24(+) cells. In order to reveal the transcripts that support the CD24(+) aggressive and invasive ...[more]