Ontology highlight
ABSTRACT:
SUBMITTER: Pallares J
PROVIDER: S-EPMC4585733 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Pallarès Jordi J Senan Oriol O Guimerà Roger R Vernet Anton A Aguilar-Mogas Antoni A Vilahur Gemma G Badimon Lina L Sales-Pardo Marta M Cito Salvatore S
Scientific reports 20150922
Thrombus formation is a multiscale phenomenon triggered by platelet deposition over a protrombotic surface (eg. a ruptured atherosclerotic plaque). Despite the medical urgency for computational tools that aid in the early diagnosis of thrombotic events, the integration of computational models of thrombus formation at different scales requires a comprehensive understanding of the role and limitation of each modelling approach. We propose three different modelling approaches to predict platelet de ...[more]