Interest of Tumor-Specific CD4 T Helper 1 Cells for Therapeutic Anticancer Vaccine.
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ABSTRACT:
SUBMITTER: Galaine J
PROVIDER: S-EPMC4586463 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
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Interest of Tumor-Specific CD4 T Helper 1 Cells for Therapeutic Anticancer Vaccine.
Galaine Jeanne J Borg Christophe C Godet Yann Y Adotévi Olivier O
Vaccines 20150630 3
Nowadays, immunotherapy represents one promising approach for cancer treatment. Recently, spectacular results of cancer immunotherapy clinical trials have confirmed the crucial role of immune system in cancer regression. Therapeutic cancer vaccine represents one widely used immunotherapy strategy to stimulate tumor specific T cell responses but clinical impact remains disappointing in targeting CD8 T cells. Although CD8 T cells have been initially considered to be the main protagonists, it is no ...[more]
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