Ontology highlight
ABSTRACT:
SUBMITTER: Briz V
PROVIDER: S-EPMC4586750 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Briz Victor V Liu Yan Y Zhu Guoqi G Bi Xiaoning X Baudry Michel M
The Journal of cell biology 20150921 7
Estrogen is an important modulator of hippocampal synaptic plasticity and memory consolidation through its rapid action on membrane-associated receptors. Here, we found that both estradiol and the G-protein-coupled estrogen receptor 1 (GPER1) specific agonist G1 rapidly induce brain-derived neurotrophic factor (BDNF) release, leading to transient stimulation of activity-regulated cytoskeleton-associated (Arc) protein translation and GluA1-containing AMPA receptor internalization in field CA3 of ...[more]