Molecular mechanisms controlling the migration of striatal interneurons.
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ABSTRACT:
SUBMITTER: Villar-Cervino V
PROVIDER: S-EPMC4589566 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Publications
Molecular mechanisms controlling the migration of striatal interneurons.
Villar-Cerviño Verona V Kappeler Caroline C Nóbrega-Pereira Sandrina S Henkemeyer Mark M Rago Luciano L Nieto M Angela MA Marín Oscar O
The Journal of neuroscience : the official journal of the Society for Neuroscience 20150601 23
In the developing telencephalon, the medial ganglionic eminence (MGE) generates many cortical and virtually all striatal interneurons. While the molecular mechanisms controlling the migration of interneurons to the cortex have been extensively studied, very little is known about the nature of the signals that guide interneurons to the striatum. Here we report that the allocation of MGE-derived interneurons in the developing striatum of the mouse relies on a combination of chemoattractive and che ...[more]
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