Ontology highlight
ABSTRACT:
SUBMITTER: Unthank JL
PROVIDER: S-EPMC4593322 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Unthank Joseph L JL Miller Steven J SJ Quickery Ariel K AK Ferguson Ethan L EL Wang Meijing M Sampson Carol H CH Chua Hui Lin HL DiStasi Matthew R MR Feng Hailin H Fisher Alexa A Katz Barry P BP Plett P Artur PA Sandusky George E GE Sellamuthu Rajendran R Vemula Sasidhar S Cohen Eric P EP MacVittie Thomas J TJ Orschell Christie M CM
Health physics 20151101 5
The threat of radiation exposure from warfare or radiation accidents raises the need for appropriate animal models to study the acute and chronic effects of high dose rate radiation exposure. The goal of this study was to assess the late development of fibrosis in multiple organs (kidney, heart, and lung) in survivors of the C57BL/6 mouse model of the hematopoietic-acute radiation syndrome (H-ARS). Separate groups of mice for histological and functional studies were exposed to a single uniform t ...[more]