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A Biomimetic Core-Shell Platform for Miniaturized 3D Cell and Tissue Engineering.


ABSTRACT: This article describes a biomimetic core-shell platform with a collagen-based core and an alginate hydrogel shell for cell and tissue culture. With this system, chemical and physical properties of extracellular matrix (ECM) in the core microenvironment can be controlled to regulate proliferation and development of cells/tissues under miniaturized three-dimensional (3D) culture.

SUBMITTER: Agarwal P 

PROVIDER: S-EPMC4594878 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature

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A Biomimetic Core-Shell Platform for Miniaturized 3D Cell and Tissue Engineering.

Agarwal Pranay P   Choi Jung Kyu JK   Huang Haishui H   Zhao Shuting S   Dumbleton Jenna J   Li Jianrong J   He Xiaoming X  

Particle & particle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems 20150512 8


<b>This article describes a biomimetic core-shell platform</b> with a collagen-based core and an alginate hydrogel shell for cell and tissue culture. With this system, chemical and physical properties of extracellular matrix (ECM) in the core microenvironment can be controlled to regulate proliferation and development of cells/tissues under miniaturized three-dimensional (3D) culture. ...[more]

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