Higher cord blood 25-hydroxyvitamin D concentrations reduce the risk of early childhood eczema: in children with a family history of allergic disease.

ABSTRACT: BACKGROUND:In recent years the role of vitamin D status in early life on the development of allergic disease has generated much interest. The aim of this study was to determine whether cord blood vitamin D concentrations were associated with risk of early childhood allergic disease. METHODS:Measurements of cord blood 25-hydroxyvitamin D [25(OH)D] concentrations were available in 270 mother-child pairs who were participating in the allergy follow-up (n = 706) of the Docosahexaenoic Acid to Optimise Mother Infant Outcome randomised controlled trial. All of the children had a hereditary risk of allergic disease. The diagnosis of allergic disease was made during medical assessments at 1 and 3 years of age. RESULTS:The mean (standard deviation) standardised cord blood 25(OH)D concentration was

SUBMITTER: Palmer DJ 

PROVIDER: S-EPMC4594897 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature