Ontology highlight
ABSTRACT:
SUBMITTER: Olmedo M
PROVIDER: S-EPMC4596660 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Olmedo María M Geibel Mirjam M Artal-Sanz Marta M Merrow Martha M
Genetics 20150820 2
Caenorhabditis elegans postembryonic development consists of four discrete larval stages separated by molts. Typically, the speed of progression through these larval stages is investigated by visual inspection of the molting process. Here, we describe an automated method to monitor the timing of these discrete phases of C. elegans maturation, from the first larval stage through adulthood, using bioluminescence. The method was validated with a lin-42 mutant strain that shows delayed development r ...[more]