Ontology highlight
ABSTRACT:
SUBMITTER: Sun S
PROVIDER: S-EPMC4598633 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Sun Shuguo S Reddy B V V G BV Irvine Kenneth D KD
Nature communications 20150930
Hippo signalling controls organ growth and cell fate by regulating the activity of the kinase Warts. Multiple Hippo pathway components localize to apical junctions in epithelial cells, but the spatial and functional relationships among components have not been clarified, nor is it known where Warts activation occurs. We report here that Hippo pathway components in Drosophila wing imaginal discs are organized into distinct junctional complexes, including separate distributions for Salvador, Expan ...[more]