Hippo signalling during development.
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ABSTRACT:
SUBMITTER: Davis JR
PROVIDER: S-EPMC7100553 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Publications
Hippo signalling during development.
Davis John Robert JR Tapon Nicolas N
Development (Cambridge, England) 20190916 18
The Hippo signalling pathway and its transcriptional co-activator targets Yorkie/YAP/TAZ first came to attention because of their role in tissue growth control. Over the past 15 years, it has become clear that, like other developmental pathways (e.g. the Wnt, Hedgehog and TGFβ pathways), Hippo signalling is a 'jack of all trades' that is reiteratively used to mediate a range of cellular decision-making processes from proliferation, death and morphogenesis to cell fate determination. Here, and in ...[more]
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