Ontology highlight
ABSTRACT:
SUBMITTER: Li N
PROVIDER: S-EPMC4600489 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Li Ning N Leung Gilberto K K GK
BioMed research international 20150927
Spinal cord injury (SCI) is a devastating condition to individuals, families, and society. Oligodendrocyte loss and demyelination contribute as major pathological processes of secondary damages after injury. Oligodendrocyte precursor cells (OPCs), a subpopulation that accounts for 5 to 8% of cells within the central nervous system, are potential sources of oligodendrocyte replacement after SCI. OPCs react rapidly to injuries, proliferate at a high rate, and can differentiate into myelinating oli ...[more]