Ontology highlight
ABSTRACT:
SUBMITTER: Maskey D
PROVIDER: S-EPMC4601663 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Maskey Dipak D Marlin Matthew Caleb MC Kim Seokho S Kim Sehyun S Ong E-Ching EC Li Guangpu G Tsiokas Leonidas L
The EMBO journal 20150723 19
Primary cilia start forming within the G1 phase of the cell cycle and continue to grow as cells exit the cell cycle (G0). They start resorbing when cells re-enter the cell cycle (S phase) and are practically invisible in mitosis. The mechanisms by which cilium biogenesis and disassembly are coupled to the cell cycle are complex and not well understood. We previously identified the centrosomal phosphoprotein NDE1 as a negative regulator of ciliary length and showed that its levels inversely corre ...[more]