Ontology highlight
ABSTRACT:
SUBMITTER: Dhanyasi N
PROVIDER: S-EPMC4602036 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Dhanyasi Nagaraju N Segal Dagan D Shimoni Eyal E Shinder Vera V Shilo Ben-Zion BZ VijayRaghavan K K Schejter Eyal D ED
The Journal of cell biology 20151001 1
Fusion of individual myoblasts to form multinucleated myofibers constitutes a widely conserved program for growth of the somatic musculature. We have used electron microscopy methods to study this key form of cell-cell fusion during development of the indirect flight muscles (IFMs) of Drosophila melanogaster. We find that IFM myoblast-myotube fusion proceeds in a stepwise fashion and is governed by apparent cross talk between transmembrane and cytoskeletal elements. Our analysis suggests that ce ...[more]