Cystatin C as a predictive marker of renal dysfunction and mid-term outcomes following off-pump coronary artery bypass grafting.

ABSTRACT:

Objective

To determine whether plasma cystatin C and creatinine levels after isolated off-pump coronary artery bypass grafting (OPCAB) are predictive of postoperative renal dysfunction and clinical outcomes.

Methods

Between January 2008 and December 2013, 1033 who underwent isolated OPCAB were recruited. The patients were divided into three groups according to the preoperative level of cystatin C: low (0.83 mg/L>), mid (0.83-1.13 mg/L) and high (1.13 mg/L<). The endpoints of all-cause mortality and major adverse cerebrovascular and cardiovascular events were compared among three groups using the Kaplan-Meier method. The predictive power of cystatin C was compared with creatinine using receiver operating curves.

Results

Follow-up was complete in all of the included pat

SUBMITTER: Lee SH 

PROVIDER: S-EPMC4602261 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature