Ontology highlight
ABSTRACT:
SUBMITTER: Chen R
PROVIDER: S-EPMC4603709 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Chen Ruiwan R Xu Yafei Y Du Xiaojing X Liu Na N Li Yingqin Y He Qingmei Q Tang Linglong L Mao Yanping Y Sun Ying Y Chen Lei L Ma Jun J
OncoTargets and therapy 20151008
The chemokine receptor 4/chemokine ligand 12 (CXCR4/CXCL12) axis plays an important role in tumorigenesis, metastasis, and recurrence of tumors. Its single nucleotide polymorphisms (SNPs) are associated with patient survival in several types of cancer. However, the prognostic value of SNPs in nasopharyngeal carcinoma (NPC) has not been fully investigated. This retrospective study assessed the relationships between CXCR4 rs2228014 and CXCL12 rs1801157 polymorphisms and patient outcome in 222 pati ...[more]