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Parsing Physiological Functions of Erythropoietin One Domain at a Time.


ABSTRACT: A domain of erythropoietin (EPO), separate from the domain involved in red blood cell development, has been identified. This region of EPO has anti-inflammatory and neuroprotective effects. Use of a peptide sequence from this region provides the potential for an effective therapeutic without effects on erythropoiesis.

SUBMITTER: Steinman L 

PROVIDER: S-EPMC4604186 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature

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Parsing Physiological Functions of Erythropoietin One Domain at a Time.

Steinman Lawrence L  

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20151001 4


A domain of erythropoietin (EPO), separate from the domain involved in red blood cell development, has been identified. This region of EPO has anti-inflammatory and neuroprotective effects. Use of a peptide sequence from this region provides the potential for an effective therapeutic without effects on erythropoiesis. ...[more]

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