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Dissemination of carbapenemase-producing Enterobacteriaceae and Pseudomonas aeruginosa in Romania.


ABSTRACT: Fifteen carbapenemase-producing Enterobacteriaceae isolates and 12 carbapenemase-producing Pseudomonas aeruginosa isolates were recovered from patients hospitalized between August 2011 and March 2013 at the Hospital of Infectious Disease, Cluj-Napoca, Romania. One KPC-, nine NDM-1-, four OXA-48-, and one VIM-4-producing Enterobacteriaceae isolates along with 11 VIM-2-producing and one IMP-13-producing P. aeruginosa isolates were recovered from clinical samples. All carbapenemase genes were located on self-conjugative plasmids and were associated with other resistance determinants, including extended-spectrum ?-lactamases and RmtC methylases.

SUBMITTER: Dortet L 

PROVIDER: S-EPMC4604391 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature

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Dissemination of carbapenemase-producing Enterobacteriaceae and Pseudomonas aeruginosa in Romania.

Dortet Laurent L   Flonta Mirela M   Boudehen Yves-Marie YM   Creton Elodie E   Bernabeu Sandrine S   Vogel Anaïs A   Naas Thierry T  

Antimicrobial agents and chemotherapy 20150824 11


Fifteen carbapenemase-producing Enterobacteriaceae isolates and 12 carbapenemase-producing Pseudomonas aeruginosa isolates were recovered from patients hospitalized between August 2011 and March 2013 at the Hospital of Infectious Disease, Cluj-Napoca, Romania. One KPC-, nine NDM-1-, four OXA-48-, and one VIM-4-producing Enterobacteriaceae isolates along with 11 VIM-2-producing and one IMP-13-producing P. aeruginosa isolates were recovered from clinical samples. All carbapenemase genes were locat  ...[more]

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