Fatty alcohols production by oleaginous yeast.
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ABSTRACT:
SUBMITTER: Fillet S
PROVIDER: S-EPMC4607723 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Publications
Fatty alcohols production by oleaginous yeast.
Fillet Sandy S Gibert Jordi J Suárez Beatriz B Lara Armando A Ronchel Carmen C Adrio José L JL
Journal of industrial microbiology & biotechnology 20150829 11
We have engineered Rhodosporidium toruloides to produce fatty alcohols by expressing a fatty acyl-CoA reductase from Marinobacter aquaeolei VT8. Production of fatty alcohols in flasks was achieved in different fermentation media at titers ranging from 0.2 to 2 g/L. In many of the conditions tested, more than 80 % of fatty alcohols were secreted into the cultivation broth. Through fed-batch fermentation in 7 L bioreactors, over 8 g/L of C(16)-C(18) fatty alcohols were produced using sucrose as th ...[more]
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