Ontology highlight
ABSTRACT:
SUBMITTER: Wang L
PROVIDER: S-EPMC4608362 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Wang Lin L Bi Chongwei C Cai Hongjun H Liu Bingrun B Zhong Xiaobo X Deng Xuming X Wang Tiedong T Xiang Hua H Niu Xiaodi X Wang Dacheng D
Frontiers in microbiology 20151016
The emergence and wide spread of multi-drug resistant Staphylococcus aureus (S. aureus) requires the development of new therapeutic agents with alternative modes of action. Anti-virulence strategies are hoped to meet that need. Sortase A (SrtA) has attracted great interest as a potential drug target to treat infections caused by S. aureus, as many of the surface proteins displayed by SrtA function as virulence factors by mediating bacterial adhesion to specific organ tissues, invasion of host ce ...[more]