Ontology highlight
ABSTRACT:
SUBMITTER: Bolick DT
PROVIDER: S-EPMC4615194 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Bolick David T DT Kolling Glynis L GL Moore John H JH de Oliveira Luís Antônio LA Tung Kenneth K Philipson Casandra C Viladomiu Monica M Hontecillas Raquel R Bassaganya-Riera Josep J Guerrant Richard L RL
Gut microbes 20140101 5
Enteroaggregative Escherichia coli (EAEC) is increasingly recognized as a major cause of diarrheal disease globally. In the current study, we investigated the impact of zinc deficiency on the host and pathogenesis of EAEC. Several outcomes of EAEC infection were investigated including weight loss, EAEC shedding and tissue burden, leukocyte recruitment, intestinal cytokine expression, and virulence expression of the pathogen in vivo. Mice fed a protein source defined zinc deficient diet (dZD) had ...[more]