Ontology highlight
ABSTRACT:
SUBMITTER: Decker B
PROVIDER: S-EPMC4617961 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Genome research 20150731 11
Canine transmissible venereal tumor (CTVT) is a parasitic cancer clone that has propagated for thousands of years via sexual transfer of malignant cells. Little is understood about the mechanisms that converted an ancient tumor into the world's oldest known continuously propagating somatic cell lineage. We created the largest existing catalog of canine genome-wide variation and compared it against two CTVT genome sequences, thereby separating alleles derived from the founder's genome from somati ...[more]