Ontology highlight
ABSTRACT:
SUBMITTER: Leder BZ
PROVIDER: S-EPMC4620731 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Leder Benjamin Z BZ Tsai Joy N JN Uihlein Alexander V AV Wallace Paul M PM Lee Hang H Neer Robert M RM Burnett-Bowie Sherri-Ann M SA
Lancet (London, England) 20150702 9999
<h4>Background</h4>Unlike most chronic diseases, osteoporosis treatments are generally limited to a single drug at a fixed dose and frequency. Nonetheless, no approved therapy is able to restore skeletal integrity in most osteoporotic patients and the long-term use of osteoporosis drugs is controversial. Thus, many patients are treated with the sequential use of two or more therapies. The DATA study showed that combined teriparatide and denosumab increased bone mineral density more than either d ...[more]