Retinoid Chemoprevention: Who Can Benefit?
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SUBMITTER: Bunaciu RP
PROVIDER: S-EPMC4628910 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
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Retinoid Chemoprevention: Who Can Benefit?
Bunaciu Rodica P RP Yen Andrew A
Current pharmacology reports 20150415 6
Acute promyelocytic leukemia (APL) is a treatment success story. From a highly deadly disease it was turned into a highly curable disease by the introduction of differentiation-induction therapy with all-trans retinoic acid (ATRA) in the 1990's. During the last quarter of century, ATRA and other retinoids were used for the treatment and prevention of other cancers and even other diseases. The results were less spectacular, but nevertheless important. Progress has been made toward understanding t ...[more]
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