Ontology highlight
ABSTRACT:
SUBMITTER: Gonzalez-Cao M
PROVIDER: S-EPMC4630555 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Annals of translational medicine 20151001 18
Targeted therapy drugs are developed against specific molecular alterations on cancer cells. Because they are "targeted" to the tumor, these therapies are more effective and better tolerated than conventional therapies such as chemotherapy. In the last decade, great advances have been made in understanding of melanoma biology and identification of molecular mechanisms involved in malignant transformation of cells. The identification of oncogenic mutated kinases involved in this process provides ...[more]