Ontology highlight
ABSTRACT:
SUBMITTER: Wang M
PROVIDER: S-EPMC4631329 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Wang Ming M Altinoglu Sarah S Takeda Yuji S YS Xu Qiaobing Q
PloS one 20151103 11
Exosomes are small, cell-secreted vesicles that transfer proteins and genetic information between cells. This intercellular transmission regulates many physiological and pathological processes. Therefore, exosomes have emerged as novel biomarkers for disease diagnosis and as nanocarriers for drug delivery. Here, we report an easy-to-adapt and highly versatile methodology to modulate exosome composition and conjugate exosomes for intracellular delivery. Our strategy combines the metabolic labelin ...[more]